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Hot sale Ibrutinib intermediate Cas 330792-70-6
 
Hot sale Ibrutinib intermediate Cas 330792-70-6
Category: Active_Pharmaceutical_Ingredient
3-Amino-5-(4-phenoxyphenyl)-4-cyano-1H-pyrazole is an intermediate used in the synthesis of ibrutinib, which is a Bruton's tyrosine kinase (BTK) inhibitor for the treatment of chronic lymphocytic leukemia (CChemicalbookLL) and mantle cell lymphoma (MCL).
Brand Name:OCEAN
Payment Terms: L/C, T/T, Western Union, Paypal
 
 

Product introduction

Product name: 5-aMino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile

Cas: 330792-70-6

MF: C16H12N4O

Appearance: Light yellow to off-white powder

Assay: ≥98.5%

Maxium single impurity: ≤1.0%

Total impurity: ≤0.2%

Loss on drying: ≤1.0%

Residue on ignition: ≤0.2%

Heavy metals: ≤20ppm

Molecular Weight: 276.29


Application: 3-Amino-5-(4-phenoxyphenyl)-4-cyano-1H-pyrazole is an intermediate used in the synthesis of ibrutinib, which is a Bruton's tyrosine kinase (BTK) inhibitor for the treatment of chronic lymphocytic leukemia (CChemicalbookLL) and mantle cell lymphoma (MCL). Ibrutinib can target BTK necessary for the formation, differentiation, information transmission and survival of B lymphocytes, irreversibly inhibit the activity of BTK, and effectively inhibit the proliferation and survival of tumor cells.


Specification

TESTS

SPECIFICATIONS

RESULTS

Appearance

Light yellow to off-white powder

Off-white poeder

Related substance

Maxium single impurity

≤1.0%

0.33%

Total impurity

≤2.0%

0.65%

Loss on drying

≤1.0%

0.49%

Residue on ignition

≤0.2%

Conforms

Heavy metal

≤20ppm

Conforms

Assay

≥98.5%

99.35%

 

Tadanafil Intermediate | Lurasidone Intermediate

Production Market
Since the establishment of our company's foreign trade export business, through the unremitting efforts of the company team, our export business has achieved very good results. Our products are exported to USA, Japan, Korea, Singapore, India, UK, Russia, France, Algeria and other countries and has got a good customer feedback and trust.

Main markets

Total revenue(%)

North America

50%

Western Europe

25%

Eastern Europe

20%

Mid East

5%

Our Factory
QINGDAO OCEAN PHARM CO.,LTD .is a leading research-driven family-managed pharmaceutical company. In the principle of “Quality Oriented”, Jianfe ng passed the certification of ISO9001:2008 Quality Management System. The products meet USP, EP, JP and CP standards and are available not only in China but also in the US, Germany, Canada, Japan, etc. To meet market demands, OCEAN set up one R&D center, two GMP standard workshops and three pharmaceutical & chemical factories

Our Service

As for pre-sales service:
1 We can provide you high quality products with factory price
2 Easy communication and comfortable cooperation
3 Better payment terms : T/T, Paypal, moneygram, credit card, etc

As for in-sales service:

1 We offer fast and safe shipping services, takes only 5-7 days.
2 Various shipping ways : by air./ by sea / by courier (FedEx)
3 Provide technical documentation support when required.

As for after-sales service:

1 Provide helps when there’s any custom issues
2 Product compensation when it’s hold in clearance

 
 
 
 
Adhering to the service tenet of "Integrity, Innovation, Harmony, and Win-win", OCEAN established a complete one-stop procurement and comprehensive solution service system.
 
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